하악 전방부에 발생한 거대 중심성 골화성 섬유종
Huge Central Ossifying Fibroma on the Anterior Mandible : A Case Report
문성용, 김수관, 김학균, 윤정훈,
소속 상세정보
문성용 ( Moon Seong-Yong ) - 조선대학교 치과대학 구강악안면외과학교실
김수관 ( Kim Su-Gwan ) - 조선대학교 치과대학 구강악안면외과학교실
김학균 ( Kim Hak-Kyun ) - 충남대학교 의과대학 치과학교실 구강악안면외과
윤정훈 ( Yoon Jung-Hoon ) - 원광대학교 치과대학 대전치과병원 구강병리과
KMID : 0829220120360040243
Abstract
The ossifying fibroma (OF), with the microscopic features of trabuclae or spherules of bone or cementum-like material in a cellular fibrous connective tissue stroma, is one of the most common benign fibro-osseous lesions in the jaw bones. The OF often occurs in patients from 20 to 40 years of age, which is a definite female predilection. The mandibles are involved far more often than the maxillas, especially the pre-molar and molar regions. It is slow-growing, bone producing, asymptomatic and well-demarcated. The OF is a disorder of odontogenesis or osteogenesis ascribed to bone marrow stroma cells (BMSCs) abnormality. However, the detailed mechanisms of OF’s oncogenesis, cytodifferentiation, and tumor progression remain unknown. In this article, we reported a huge central OF on the anterior mandible. The lesion was enucleated and peripheral ostectomy was done via intraoral approach and reconstructed with vascularized iliac block bone graft. After 25 months of follow up, the tumor had not recurred. This case shows that OF may be successfully treated by conservative surgical enucleation and peripheral ostectomy.
키워드
Ossifying fibroma; Mandible; Surgical enucleation
원문 및 링크아웃 정보
등재저널 정보